{"product_id":"mazdutide-10vials-box","title":"Mazdutide 10vials\/box","description":"\u003cp data-pm-slice=\"1 1 []\"\u003eProduct Basic Information\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eFull Name: Mazdutide (Development Code IBI362, LY3305677)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eEssence: A GLP-1R\/GCGR dual receptor agonist, a synthetic peptide analog of mammalian oxyntomodulin (OXM)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eForm: Sterile lyophilized peptide powder, individually packaged in vials\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eUses: In vitro research reagents related to metabolic syndrome, obesity, type 2 diabetes, and non-alcoholic fatty liver disease (MASLD)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eII. Mechanism of Action\u003c\/p\u003e\u003cp\u003eMazdutide has a dual-target synergistic effect, achieving dual metabolic regulation of \"inhibiting intake + increasing consumption\" by balancing the activation of GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR):\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eGLP-1R Pathway (\"Blocking\"): Acts on the central nervous system and gastrointestinal tract, inhibiting appetite, delaying gastric emptying, and reducing food intake; simultaneously promoting pancreatic glucose-dependent insulin secretion, lowering blood glucose.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eGCGR Pathway (“Breakthrough”): Targets the liver and brown adipose tissue, increasing basal metabolic rate, promoting lipid oxidation and decomposition, and reducing hepatic lipid deposition, overcoming the limitation of single GLP-1 agonist-based weight loss relying solely on “eating less”.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eMolecular Characteristics: Modified with fatty acid side chains, resulting in a significantly prolonged half-life, suitable for long-acting research models with weekly dosing.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eIII. Core Research Efficacy\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003ePowerful Weight Loss: In in vitro models, it synergistically inhibits food intake and increases energy expenditure, significantly reducing weight, waist circumference, and body fat percentage, superior to single GLP-1 agonist controls.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eGlucose Regulation: Promotes insulin secretion, improves insulin sensitivity, and reduces glycated hemoglobin (HbA1c), suitable for research on the mechanisms of type 2 diabetes.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eLiver Protection: Reduces hepatic fat accumulation, lowers transaminase levels, improves pathological indicators of non-alcoholic fatty liver disease (MASLD), and inhibits intrahepatic inflammation and endoplasmic reticulum stress.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eComprehensive Metabolic Improvement: Reduces blood lipids, uric acid, and blood pressure, improves multiple cardiovascular metabolic risk factors, suitable for comprehensive intervention research on metabolic syndrome.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eLong-acting model adaptation: Supports weekly dosing in vitro\/animal long-acting dosing regimens, simplifying experimental design and operation.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eIV. Reconstitution and Storage Specifications\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eReconstitution solvent: Sterile water for injection, 0.6% acetic acid aqueous solution for preparing the experimental working solution.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eStorage requirements: Unopened lyophilized powder: Store at 2-8℃, protected from light, sealed, and refrigerated. Keep away from moisture and high temperatures. Freezing is strictly prohibited.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eReconstituted liquid: Refrigerate at 4℃, protected from light.\u003c\/p\u003e","brand":"mySite","offers":[{"title":"Default Title","offer_id":42723870212142,"sku":"dlz1789826548204","price":258.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0605\/8275\/6398\/files\/b02d1a026583aa5da097f0aa35adacc8b434582a05812c41eaf6e768518ebd14.webp?v=1789826854","url":"https:\/\/yuanpeptide.shop\/products\/mazdutide-10vials-box","provider":"YUANPeptide","version":"1.0","type":"link"}