{"product_id":"mgf-10vials-box","title":"MGF 10vials\/box","description":"\u003cp data-pm-slice=\"1 1 []\"\u003eMGF (Mechano Growth Factor, IGF-1Ec) Internal Product Introduction (No Injection Dosage, Includes a Standard Disclaimer)\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eI. Basic Product Information\u003c\/p\u003e\u003cp\u003eFull Name: MGF (Mechano Growth Factor), a muscle\/mechanical stress-specific IGF-1 splice variant (human IGF-1Ec, rodent IGF-1Eb)\u003c\/p\u003e\u003cp\u003eCore Active Fragment: C- terminal 24-amino acid E peptide (Ec peptide), the key functional region\u003c\/p\u003e\u003cp\u003eAmino Acid Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-NH₂\u003c\/p\u003e\u003cp\u003eCAS Number: No publicly available standard CAS (Specifically for Scientific Research Peptides)\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eMolecular Formula: C₁₂₄H₂₀₄N₄₂O₄₁S₁\u003c\/p\u003e\u003cp\u003eMolecular Weight: Approx. 2972 Da\u003c\/p\u003e\u003cp\u003eAppearance: White\/off-white sterile lyophilized powder, good water solubility\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eUses: Reagent for in vitro scientific research experiments related to muscle satellite cell activation, muscle fiber repair and hypertrophy, sports injury repair, age-related sarcopenia, cartilage\/bone regeneration, and cardiomyocyte protection\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eII. Mechanism of Action\u003c\/p\u003e\u003cp\u003eMechanism of Action\u003c\/p\u003e\u003cp\u003eMechanical Stress Response and Local Activation (Core): When muscles are subjected to mechanical stretching, injury, or hypoxia, the IGF-1 gene undergoes selective splicing, rapidly expressing MGF; its unique C- terminal E peptide, independent of the mature IGF-1 structure, activates the signaling pathway through an unknown specific receptor (non-IGF-1R).\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eSatellite Cell Proliferation Regulation: Preferentially activates resting muscle satellite cells (muscle stem cells), promoting their rapid proliferation, expanding the muscle precursor cell pool, inhibiting premature differentiation, and reserving a large number of cell sources for muscle fiber repair.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eMuscle fiber repair and hypertrophy: Accelerates the regeneration of damaged muscle fibers, increasing muscle fiber cross-sectional area and muscle mass; enhances muscle adaptability to mechanical loads and promotes post-exercise supercompensation.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eAnti-apoptosis and tissue protection: Inhibits apoptosis of myocytes, chondrocytes, and cardiomyocytes, reducing cell death caused by injury, aging, and oxidative stress.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eCross-tissue repair effects: Acts on chondrocytes, promoting their proliferation, migration, and matrix synthesis, repairing articular cartilage damage; provides protection for cardiomyocytes, improving ischemia-reperfusion injury.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eReversal of aging muscle function: Reverses the decline in MGF expression in aging muscles, restores the responsiveness of satellite cells to mechanical stimulation, and delays the progression of sarcopenia.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eIII. Core Research Efficacy\u003c\/p\u003e\u003cp\u003eSports Injuries and Postoperative Repair: In vitro mechanism research for muscle strains, tears, post-exercise micro-injuries, and post-orthopedic surgery muscle\/cartilage repair.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eSarcopenia and aging muscle research: Explores intervention strategies for aging muscle atrophy, strength decline, and satellite cell function deterioration.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e* **Muscle Hypertrophy and Resistance Training Mechanisms:** Investigating the molecular pathways and local regulatory targets of resistance training-induced muscle mass growth and strength enhancement.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e* **Cartilage and Bone Regeneration:** Studying the repair mechanisms of osteoarthritis, cartilage defects, and fracture healing.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e* **Myocardial Protection and Ischemia Repair:** Developing research models for myocardial cell protection and functional recovery after myocardial ischemia and myocardial infarction.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e* **Combined Research Systems:** Often combined with BPC-157, TB-500, Cortagen, and Chonluten to construct multi-target tissue repair complex research protocols involving muscle, cartilage, nerves, and immunity.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e* **IV. Reconstitution and Storage Specifications:**\u003c\/p\u003e\u003cp\u003e**Reconstitution Solvents:** Sterile water for injection, physiological saline, or 0.9% sodium chloride solution can all be used.\u003c\/p\u003e\u003cp\u003e* **Storage Requirements:**\u003c\/p\u003e\u003cp\u003e**Unopened Lyophilized Powder:** Store at -20°C protected from light. Shelf life: 12-24 months.\u003c\/p\u003e\u003cp\u003e**Reconstituted Liquid:** Store at 4°C protected from light.\u003c\/p\u003e","brand":"mySite","offers":[{"title":"Default Title","offer_id":42723865526318,"sku":"dlz1789826526067","price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0605\/8275\/6398\/files\/d1315859f23d276226c28e83dd2041b5345c794ee44d86de46fca02dd44a3b40.webp?v=1789826817","url":"https:\/\/yuanpeptide.shop\/products\/mgf-10vials-box","provider":"YUANPeptide","version":"1.0","type":"link"}