{"product_id":"nad-10vials-box","title":"NAD 10Vials\/box","description":"\u003cp data-pm-slice=\"1 1 []\"\u003eBasic Information\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eFull Name: Nicotinamide Adenine Dinucleotide (NAD+, oxidized form)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eCAS: 53-84-9\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eStructure: A dinucleotide composed of nicotinamide + adenine + two ribose + two phosphate groups, the active form of vitamin B3.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eForms: Oxidized form (NAD+, electron acceptor), reduced form (NADH, electron donor); the NAD+\/NADH ratio determines the cellular metabolic state.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eHalf-life: Minutes to hours (rapid turnover, requires continuous synthesis)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eState: Endogenous molecule in the human body, not a drug; supplementation is mainly through oral\/injection progenitor.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eII. Core Mechanism of Action\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e1. Energy Metabolism Center (ATP Production)\u003c\/p\u003e\u003cp\u003eAs an electron carrier, it participates in glycolysis, the tricarboxylic acid cycle, and fatty acid oxidation, transferring electrons from metabolites to the mitochondrial respiratory chain, generating over 95% of ATP. NAD+ is reduced to NADH, and NADH is then oxidized back to NAD+, driving energy production in a cyclical process.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e2. Activation of Sirtuins Longevity Protein (Core Anti-Aging Pathway)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eIt is the only essential coenzyme of **SIRT1-7 (Silencing Information Regulator)**\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eSirtuins regulate: DNA repair, mitochondrial biosynthesis, inflammation suppression, biological clock, and autophagy, directly delaying cellular aging.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e3. DNA Repair and Genome Stability\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eProvides substrates for **PARP (Polyadecto-ribose diphosphate polymerase)**, repairing DNA single\/double strand breaks and preventing gene mutations and apoptosis.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eDuring aging\/stress, excessive PARP activation consumes NAD+, forming a vicious cycle of \"aging - decreased NAD+ - weakened repair\".\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e4. Metabolic Reprogramming and Signal Regulation\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eRegulates the AMPK\/mTOR pathway, improving insulin sensitivity, promoting lipid oxidation, and inhibiting lipid synthesis.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eParticipates in calcium ion signaling, neurotransmitter synthesis, and immune regulation, maintaining systemic homeostasis.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eIII. Core Efficacy (Research\/Clinical)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e1. Boosting Energy and Combating Fatigue\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eEnhances mitochondrial function, eliminates chronic fatigue, boosts energy, and improves exercise endurance.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eRelieves afternoon fatigue and recovery after staying up late.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e2. 3. **Delaying Aging and Cell Rejuvenation:**\u003c\/p\u003e\u003cp\u003eActivates Sirtuins, reducing wrinkles, improving skin elasticity, and delaying organ aging.\u003c\/p\u003e\u003cp\u003eEnhances telomere stability and reduces cell apoptosis.\u003c\/p\u003e\u003cp\u003e4. **Metabolic Health (Fat Loss\/Blood Sugar Control):**\u003c\/p\u003e\u003cp\u003eImproves insulin resistance, lowers blood sugar and glycated hemoglobin (HbA1c).\u003c\/p\u003e\u003cp\u003ePromotes the browning of white adipose tissue, increases thermogenesis, and reduces visceral fat.\u003c\/p\u003e\u003cp\u003eOptimizes blood lipids, lowers triglycerides and LDL, and increases HDL.\u003c\/p\u003e\u003cp\u003e5. **Neurological and Cognitive Protection:** Supports neuronal energy metabolism, improving memory, concentration, and sleep quality.\u003c\/p\u003e\u003cp\u003ePotentially delays the progression of Alzheimer's and Parkinson's diseases.\u003c\/p\u003e\u003cp\u003e6. **Tissue Repair and Anti-Inflammation:**\u003c\/p\u003e\u003cp\u003eAccelerates the repair of muscle, tendon, and joint damage.\u003c\/p\u003e\u003cp\u003eInhibits chronic inflammation (TNF-α, IL-6), improving inflammation-related diseases.\u003c\/p\u003e\u003cp\u003e7. **IV. NAD+ Levels and Age (Key Patterns):**\u003c\/p\u003e\u003cp\u003e20 years old: Peak NAD+ levels in the body.\u003c\/p\u003e\u003cp\u003e40 years old: Decreases to 50% of the level at age 20.\u003c\/p\u003e\u003cp\u003e60 years old: Decreases to 20% of the level at age 20. The decline in 10-20% of the age group is due to: decreased NAMPT (rate-limiting enzyme in synthesis) activity, excessive PARP depletion, and increased inflammation and oxidative stress.\u003c\/p\u003e","brand":"mySite","offers":[{"title":"NJ100 100mg 10Vials\/box","offer_id":42723868999726,"sku":"dlz1789826541865","price":40.0,"currency_code":"USD","in_stock":true},{"title":"NJ500 500mg 10Vials\/box","offer_id":42723869032494,"sku":"dlz1789826541866","price":80.0,"currency_code":"USD","in_stock":true},{"title":"NJ1000 100mg 10Vials\/box","offer_id":42723869065262,"sku":"dlz1789826541867","price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0605\/8275\/6398\/files\/17299fbd31fbd2fbf9a1d0140fa85dd8d676ddb3fac437167d9b94aa50646510.webp?v=1789826845","url":"https:\/\/yuanpeptide.shop\/products\/nad-10vials-box","provider":"YUANPeptide","version":"1.0","type":"link"}