Adamax 10vials/box
Basic Information
Full Name: Ac-MEHFPG-AG-NH₂ (N-acetylated + adamantane-modified Semax derivative)
Sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-Ala-Gly-OH
Molecular Weight: ≈984-1032 Da
Dosage Form: Lyophilized Powder
II. Core Structure and Advantages (Stronger than Semax)
N-acetylation: Improves stability, resists enzymatic degradation, and prolongs half-life
C-terminal adamantane: Significantly improves lipid solubility, with a blood-brain barrier penetration rate significantly higher than Semax. Protects peptide chains from rapid degradation, resulting in a longer-lasting effect.
Essence: An optimized version of the ACTH (4-10) fragment, preserving neural activity and enhancing brain targeting.
III. Core Mechanism (Triple Brain-Body Synergy)
BDNF-TrkB Pathway (Core)
Activates TrkB Receptors significantly upregulate BDNF (brain-derived neurotrophic factor)
Promotes neuronal survival, synaptic plasticity, and long-term memory (LTP) formation
Improves learning, memory, concentration, and mood
Neuroprotection and anti-apoptosis
Activates PI3K/Akt and CREB, inhibits neuronal apoptosis, and repairs damaged nerves
Activates Nrf2/ARE, enhances antioxidant enzymes, scavenges free radicals, and protects the brain and muscles
Anti-fatigue and athletic performance
Accelerates central nervous system (CNS) recovery and relieves nerve fatigue after high-intensity training
Enhances mitochondrial ATP production, improves endurance, and delays exercise fatigue
Improves insulin sensitivity, optimizes glucose and lipid metabolism, and aids in fat loss and energy maintenance
IV. Core Efficacy (Research/Application Scenarios)
1. Cognitive Enhancement (Main Feature)
Concentration/Clarity of Thought: Improves brain processing speed, reduces distraction, suitable for high-intensity mental work
Learning/Memory: Enhances hippocampal function, improves short-term and long-term memory
Mood/ 1. **Anti-anxiety:** Regulates neurotransmitters, improves mood, and relieves stress and anxiety.
2. **Neural Repair:** Supports the repair of brain damage, aging, and neurodegenerative changes (scientific research).
3. **Sports and Fitness (Fitness/Competition):**
Anti-neural fatigue: Rapidly restores the CNS, improving training quality and frequency.
4. **Endurance Enhancement:** Increases ATP, delays lactic acid buildup, and improves athletic performance.
5. **Accelerated Recovery:** Reduces muscle soreness and promotes post-workout recovery.
6. **Fat Loss Assistance:** Improves insulin sensitivity, accelerates fat oxidation, and maintains energy levels.
7. **Other Potential:**
Anti-brain aging: Delays cognitive decline and protects neurons.
Neuropathy/Neuropathy: Assists in repairing damaged nerves and relieves pain (scientific research).
8. **Dosage and Administration (Scientific Research Protocol)**
9. **Reconstitution:**
Solvent: 0.9% benzyl alcohol antibacterial water (BAC Water), 1-2 mL to dissolve 5-10 mg.
Instructions: Pour along the bottle wall, gently swirl to mix, do not shake vigorously.
Storage: Refrigerate at 2–8°C after reconstitution.