Aicar 10vials/box

Product Basic Information

Full Name: AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide)

Appearance: White powder, can be prepared into sterile experimental solutions

Uses: In vitro research reagent related to cellular energy metabolism, AMPK pathway activation, endurance, and lipid and glucose metabolism

II. Mechanism of Action

AICAR is a classic activator of the AMPK signaling pathway. It mimics a low-energy state in cells, upregulates AMPK expression, and regulates multiple metabolic pathways including mitochondrial formation, fatty acid oxidation, and glucose uptake. It is widely used in research on exercise metabolism, obesity, and insulin resistance cell models.

III. Core Scientific Efficacy

* Strongly activates the AMPK pathway, increases mitochondrial quantity and activity, and enhances cellular energy supply efficiency.

* Accelerates fatty acid oxidation and decomposition, reduces cellular lipid accumulation, and is suitable for lipid metabolism and fat reduction-related control experiments.

* Promotes cellular glucose uptake and utilization, improves insulin resistance-related indicators, and is used for research on glucose metabolism mechanisms.

* Reduces oxidative stress damage, alleviates cellular inflammation, and enhances cellular tolerance to fatigue and hypoxia.

* Inhibits excessive glycogen consumption, maintains sustained cellular energy output, and is suitable for endurance-related in vitro model experiments.

IV. Preparation and Storage Specifications

* Preparation Solvents: Sterile pure water and 0.6% acetic acid aqueous solution can be used to dissolve and dilute the experimental working solution.

* Storage Requirements

* Unopened Powder: Store at room temperature, protected from light, dry, and sealed. Avoid moisture and high temperatures.

* Prepared Liquid: Store at 2-8℃, protected from light.