CJC 1295 (without DAC) 10vials/box

Basic Information

Full Name: CJC-1295 without DAC (Drug-Free Affinity Complex), also known as Mod GRF 1-29 (Modified Growth Hormone Releasing Factor 1-29)

CAS: 863288-34-0

Structure: A synthetic GHRH analogue of 29 amino acids, mutated at 4 sites (D-Ala², Gln⁸, Gln¹⁵, Leu²⁷) to resist DPP-IV degradation and improve stability.

Half-life: Approximately 30 minutes (short-acting, pulsatile release)

Appearance: White lyophilized powder

II. Core Mechanism of Action (Key Difference from the DAC-Modified Version)

Mimizes natural GH pulse

Binding to pituitary GHRH receptors, stimulating a single, brief, high-amplitude GH pulse (peaks at 20-40 minutes, lasting 90-120 minutes)

Without DAC modification, it does not continuously increase GH, avoiding pituitary desensitization and negative feedback inhibition.

Synergistically works with GHRP (such as...) Ipamorelin

CJC-1295 (GHRH pathway) Ipamorelin (Ghrelin pathway) = 1 1>3, significantly increasing GH pulse amplitude and IGF-1 levels

Downstream Effects

Increase IGF-1, promoting muscle synthesis, fat breakdown, tissue repair, sleep quality, and anti-aging

III. Core Efficacy (Research/Application)

1. Muscle Growth and Body Composition Optimization

Increase lean body mass, reduce body fat (especially visceral fat), and preserve muscle

Improve strength, endurance, and athletic performance

2. Exercise Recovery and Injury Repair

Accelerate the repair of muscle tears, tendon/ligament injuries, and joint strain

Shorten post-training recovery time and reduce DOMS (Delayed Onset Muscle Soreness)

3. Anti-aging and Metabolic Health

Improve skin elasticity, reduce wrinkles, and improve sleep quality

Mildly improve insulin sensitivity, blood lipids, and bone density