Epithalon 10vials/box

Basic Information

Full Name / Aliases: Epithalon, Epitalon, Epithalamin (natural homolog), AEDG peptide

Sequence: Ala-Glu-Asp-Gly (Ala-Glu-Aspartic-Gly)

CAS: 307297-39-8 (Khavinson team), over 40 years of research

Dosage Form: Lyophilized powder

II. Core Mechanism of Action (Three Major Pathways)

1. Telomerase Activation (Most Core)

Upregulates **hTERT (telomerase reverse transcriptase)** gene expression, activates telomerase, prolongs/maintains telomere length, and delays cell senescence and apoptosis.

Breaks through the Hayflick limit of cell division, prolonging cell lifespan.

Animal studies show it can prolong lifespan by 10-25% and reduce the incidence of age-related diseases.

2. Pineal Gland and Circadian Rhythm Regulation

Promotes melatonin synthesis in the pineal gland, improving sleep and regulating circadian rhythms, especially suitable for sleep disorders in the elderly.

Restores endocrine balance and improves hormone levels (such as growth hormone and cortisol).

3. Antioxidant, DNA Repair, and Immune Regulation

Scavenges free radicals, reduces oxidative stress, and protects DNA.

Enhances immune cell activity, regulates inflammatory factors, and improves immune function.

Studies show it can reduce tumor incidence ("Epithalon Paradox": activates telomerase but inhibits tumors).

III. Main Efficacy (Research + Clinical)

Anti-aging/Longevity: Extends telomeres, delays cellular aging, and increases healthy lifespan.

Improved Sleep: Increases deep sleep, faster sleep onset, and more stable circadian rhythm.

Cognitive Enhancement: Improves memory, attention, and brain function, and delays brain aging.

Immune Enhancement: Enhances resistance, reduces infection, and regulates inflammation.

Metabolic Optimization: Improves insulin sensitivity, blood lipids, and body composition.

DNA Protection: Anti-radiation and anti-DNA damage, suitable as an adjunct to radiotherapy and chemotherapy (research).