IGF-1LR3 10vials/box

Product Basic Information

Full Name: Long R3 Insulin-like Growth Factor-1, abbreviated as IGF-1 LR3

Form: Sterile lyophilized peptide powder, individually packaged in vials

Uses: Reagent for in vitro scientific research experiments related to cell proliferation, muscle growth, tissue repair, aging mechanisms, and metabolic regulation

II. Mechanism of Action

IGF-1 LR3 is a long-acting modified variant of IGF-1 peptide. The amino acid sequence modification significantly reduces its binding affinity to IGF-binding proteins, resulting in enhanced in vitro stability. It regulates cell proliferation, differentiation, apoptosis, and protein synthesis by activating the PI3K/Akt/mTOR signaling pathway, and is widely used in research on muscle, bone, skin, and metabolic-related cell models.

III. Core Scientific Efficacy

* Strongly promotes the proliferation and differentiation of various somatic cells, accelerates the growth of muscle cells, fibroblasts, and chondrocytes, suitable for in vitro experiments on tissue regeneration and muscle hypertrophy.

* Activates protein synthesis pathways, inhibits protein breakdown, and improves lean tissue-related indicators, suitable for research on sarcopenia and the mechanisms of exercise muscle.

* Promotes the repair of damaged cells, reduces apoptosis, and lowers oxidative stress damage, suitable for controlled experiments on trauma and soft tissue repair.

* Synergistically regulates glucose and lipid metabolism, improves cellular glucose uptake efficiency, and assists in research on insulin resistance and obesity-related metabolic topics.

* Regulates bone cell activity and promotes osteoblast activity, suitable for in vitro models related to bone development and bone injury repair.

IV. Reconstitution and Storage Specifications

* Reconstitution solvent: May be prepared and dissolved using a 0.6% aqueous acetic acid solution or sterile water for injection.

* Storage Requirements

* Unopened lyophilized powder: Store at 2-8℃ protected from light. Freezing is strictly prohibited; freezing will destroy the spatial structure of the peptides and directly cause loss of biological activity.

* Reconstituted liquid: Store at 4℃ protected from light.