Thymosin Alpha-1 10vials/box

Product Basic Information

Full Name: Thymosin Alpha-1, abbreviated as Tα1

Amino Acid Sequence: 28 amino acid synthetic polypeptide, N-terminal acetylated modification

Form: White sterile lyophilized powder, individually aliquoted into vials, good water solubility

Research Applications: Thymic immune regulation, T lymphocyte differentiation, antiviral immunity, tumor immunity, inflammation balance, radiotherapy and chemotherapy-related immunoprotection in vitro cell/animal experimental reagents

II. Mechanism of Action

Thymic T Cell Maturation Induction

Targets thymic epithelial cells, promotes the differentiation and maturation of CD4/CD8 positive T lymphocyte precursors, rebuilds the peripheral immune cell pool, and reverses immune decline caused by thymic atrophy.

Denitic Cell and Antigen Presentation Activation

Enhances dendritic cell maturity, strengthens antigen presentation capacity, upregulates MHC molecule expression, and amplifies specific immune responses.

Cytokine Balance Regulation

Promotes the secretion of Th1-type factors (IL-2, IFN-γ), moderately inhibits excessive Th2 inflammatory responses, balances the body's immunity, and improves immune imbalance.

Broad-spectrum antiviral pathway activation: Upregulates endogenous antiviral substances such as interferon and defensins, inhibits DNA/RNA viral replication, and enhances the body's ability to resist viral infection.

Tumor microenvironment immune remodeling: Reduces immunosuppressive factors in the tumor microenvironment, enhances the killing activity of NK cells and cytotoxic T cells, and eliminates tumor immune escape.

Antioxidant and antiapoptotic effects: Reduces oxidative stress damage to immune cells and decreases lymphocyte apoptosis induced by radiotherapy, chemotherapy, and inflammation.

III. Core Scientific Research Achievements

Post-infection Immune Reconstitution: Immune repair models for viral infections, chronic infections, and recurrent respiratory infections;

Tumor Immunotherapy Experiments: Research on the combined intervention mechanism of immunotherapy for various solid tumors and hematological malignancies;

Bone Marrow/Immune Protection from Chemotherapy and Radiotherapy: Reducing lymphopenia and immunosuppression caused by chemotherapy and radiotherapy;

Autoimmune Balance Research: Used for in vitro controlled experiments related to chronic low-grade inflammation and immune disorders;

Aging-Related Immune Models: Exploring intervention targets for thymic function degeneration and decreased immunity due to aging;

Combined Therapy Systems: Often combined with Crystagen, BPC-157, Glutathione, and Bronchogen to construct a combined immunotherapy + mucosal + antioxidant experimental protocol.

IV. Reconstitution and Storage Guidelines

Reconstitution Solvents: Gently dissolve in sterile water for injection, physiological saline, or 0.6% acetic acid aqueous solution. Avoid vigorous shaking to prevent damage to the peptide chains;

Storage Requirements

Unopened Lyophilized Powder: Store at 2-8°C, protected from light and sealed. Long-term storage is recommended at -20°C;

Reconstituted Liquid: Store at 4°C, protected from light.